6. - Oxidative Stress
Have you ever cut an apple in half and noticed how quickly
it turns brown? Or perhaps seen how quick rust can form on a steel can which got wet and was left outside for
a day? This is oxidation occurring right before your eyes. Oxygen is life giving, and we would quickly die
without it. However, oxygen can also cause stress as you are about to see.
Your body produces large numbers of
potentially dangerous and destructive "free radical" oxygen molecules right around the clock just by your eating
and breathing. Your blood stream is filled with these free-radicals at any time, and their destructive power comes
from the fact that each of these free radicals has a single un-paired electron. These unbalanced molecules need
another electron to balance themselves out. These highly unstable particles "steal" electrons from other parts of
the body, and this damages genes, proteins and lipoproteins and can seriously raise your risk of heart disease and
cancer.
Oxidative stress occurs when your body’s natural antioxidant defenses are being overwhelmed, and there are just too
many free radicals in your system. We simply can't stop this process,
our bodies continually produce these free radicals naturally when we breathe,
digest food and neutralise alcoholic and drugs of any type, and even when cells convert fat and carbohydrates into energy. When free radicals attack LDL cholesterol, it converts into the form that
promotes atherosclerosis.
Why Does It
Happen?
Free radicals are
usually mopped up by the body’s natural antioxidant system,
particularly if your diet is very rich in "anti" oxidant foods like fresh fruits and
vegetables. If that protective system is overwhelmed, free radicals begin
to damage cells and other molecules, leading to atherosclerosis, cancer, mental decline and other health
problems. Your natural antioxidants are overwhelmed by a lack of fruit and vegetables, an excess of stress
and too little exercise.
So, if
you drink copious quantities of alcohol, exercise very little, stress and
worry too much, get too anxious, have metabolic syndrome and opt for a fast food diet such as fish and chops and cola drinks too often, this free
radical clean up simply won't happen.
Other causes of free
radical damage appear to be too much ultra violet (sun) light, tobacco smoke, too many drugs - whether
they be prescription, over-the-counter or illegal drugs, environmental toxins like sprays, chemicals, or workplace chemicals like
solvents, fuel, paint, welding, etc. Whenever your body's natural anti-oxidant defence becomes overwhelmed, you
will develop oxidative stress.
Here is a picture showing you the body's systems and how they are all affected by oxidative
stress.

Oxidative stress could hold the
key
According to
researchers oxidative stress may possibly be what switches atherosclerosis
from ‘off’ to ‘on’. You will have read about LDL already on this website,
and how it is considered the "bad" cholesterol. The critical thing to learn about oxidative stress is about when
LDL particles become oxidised themselves. Low density lipoproteins carry a greater amount of fat (cholesterol) than
their HDL brothers, but once they become oxidised, their cargo of cholesterol becomes more deadly. Oxidised LDL
(LDL-ox ) can much more readily penetrate artery walls and end up
forming artery-clogging plaque.
Your immune system's
cells called macrophages recognise these oxidised LDL's as foreign invaders and trap them so that they become
foam-filled cells that lay the foundation for plaque. LDL-ox end up making plaque grow larger and more rapidly, and eventually lead to major risk for clots,
thrombosis and a stroke. Japanese research discovered that high levels of LDL-ox
can more than double your risk of a heart attack! They also found out that those who
did have a heart attack had levels of LDL-ox up to
four times higher than those in the healthy heart
group.
Doctors who understand oxidative
stress today know that reducing a person's risk of heart disease is much more than just "lowering
cholesterol" - it is more about preventing oxidative stress by encouraging their patients to eat a diet rich
in antioxidants, fruits and vegetables. These are the foods richest in antioxidants and therefore most likely
to confer benefits, reducing the risk of oxidative
stress.
You can read a lot more about
oxidative
stress on our naturopath.co.nz
website.
Antioxidant foods are
best
People who eat ample fresh fruits and
vegetables have low levels of LDL-ox . Oxidative stress is an important heart disease mechanism
generally overlooked by medical practitioners and cardiologists in favour
of cholesterol lowering treatments. Japanese research has found that people who have had a heart attack had
levels of oxidised LDL four times higher than those in a healthy control
group. Isn't it time we looked at
the whole picture when it comes to the prevention of heart disease, instead of following the same old
line. It all makes
sense.
Your main risk factors
Oxidative stress may be more of a threat
to your heart than you think right now, the more risk factors you have, the higher the odds are that free
radicals are damaging your cardiovascular system right now.
-
Smoking
-
Being overweight
-
Metabolic syndrome or diabetes
-
Too little exercise
-
A diet very low in fruits and
vegetables
-
Mental or emotional stress
-
Poor ability to relax, too much
worry
HDL protects LDL from oxidative
damage
It is important to
raise your HDL levels fro several reasons. HDL confers several protective roles over LDL in your body,
including:
-
HDL helps move LDL to the
liver - The liver then goes on to process the
LDL and moves it to the digestive system for excretion. This is one of the reasons why you need good
fibre levels to lower your bad cholesterol!
-
HDL protects LDL - By repairing LDL by
way of siphoning off the oxidised fats.
Do you have metabolic
syndrome?
Having metabolic syndrome only increases the odds
that the LDLs you have will be much more easily oxidised. Extra fat will be more likely to be floating throughout
the circulation, coupled with continuing high levels of insulin. Extra fat for several hours after a meal can mean
that ordinary LDLs can more easily oxidise and turn into small, lethal and dense oxidised LDLs.
Having normal LDL levels can give you a false sense
of security, because you don't know what oxidised LDLs you have, and nor does your doctor! There are certain
sophisticated tests which can reveal this marker, but here's an easier way: If your blood tests reveal low HDLs and high triglycerides, then you probably
have a high level of oxidised small LDLs as well.
The bottom line is, if you do have metabolic
syndrome, you will probably have a degree of oxidisation going on in your body on different levels, and it is in
your best interests to exercise and eat the right foods!
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Key things
you need
to know about
Oxidative Stress
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How oxidative stress
happens - Free radicals attack LDL cholesterol, the free
radical damage helps convert LDLs into an oxidised form,
a lethal form that triggers or even worsens atherosclerosis. This new form of "bad"
cholesterol can also contribute to plaque formation and bursting; and it is this burst plaque that can cause
blood clots that block blood flow to the brain or heart and cause a stroke (brain) or heart
attack.
Detecting oxidative
stress -There is no test available to determine the level of oxidative stress going on in your circulatory
system, but the lifestyle choices you make on a daily basis will dictate your level of oxidative stress .
Being overweight, high stress levels, no relaxation, having a diet low in fruit and vegetables, smoking, alcohol
consumption and the use of chemicals and toxins in your home or work place including a lack of exercise
all raise your risk of oxidative stress.
Mental and emotional stress-Mental and emotional stress can boost oxidative
stress; relaxation can lower it. Metabolic syndrome is connected with stress and adrenal fatigue, so it makes sense
to look at ways of reducing your stress levels.
Standard medical care for oxidative stress- Your orthodox medical doctor or specialist can offer no effective treatment
to help reduce oxidative stress. The best way for you to begin combating this problem is to eat a diet laden in
antioxidant rich foods, particularly fresh fruits and vegetables. Anti-oxidant supplements help as well, but are
not supported by conventional "research" which has vested pharmaceutical dollar
interests. Each year,
Australians and New Zealanders spend many millions of dollars on over-the-counter vitamin and mineral
supplements—including popular antioxidants such as vitamins A, C, E and beta carotene and the minerals zinc and
selenium. Research is now validating the effectiveness of antioxidants, in particular vitamin C. We recommend that
you take in vitamins A, C and E regularly through a nutritional supplement.
What you can do
about it - Extremely high for most people, because like
metabolic syndrome, oxidative stress is a dietary and lifestyle choice. Consume foods rich
in natural antioxidants - the
colourful fruits and vegetables. In addition, exercise daily (walking is great), and look at ways to reduce your
stress. Easy food switches that will boost your daily antioxidant intake include drinking apple or grape
juice instead of soft (fizzy or carbonated) drinks, adding fresh and raw fruits and vegetables to your salad.
reduce your intake of fried and especially deep fried foods - these increase oxidation in your
body.
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